Preclinical Safety Evaluation of Inhaled Cyclosporine in Propylene Glycol
Abstract
Cyclosporine inhalation solution has the potential to improve outcomes following lung transplantation by delivering high concentrations of an immunosuppressant directly to the allograft while minimizing systemic drug exposure and associated toxicity. The objective of these studies was to evaluate the potential toxicity of aerosolized cyclosporine formulated in propylene glycol when given by inhalation route to rats and dogs for 28 days....
Paper Details
Title
Preclinical Safety Evaluation of Inhaled Cyclosporine in Propylene Glycol
Published Date
Dec 1, 2007
Journal
Volume
20
Issue
4
Pages
417 - 428
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Notes
History