Genotyping of human neutrophil antigen‐5a (Ond)
Abstract
summary . Antibodies to human neutrophil alloantigens (HNA) can cause immune‐mediated neutropenias and transfusion complications. The diagnosis of antibodies to the HNA‐5a (Ond) isoform of the α L β 2 integrin is hampered by the lack of reliable methods for HNA‐5a antigen typing. We have devised a polymerase chain reaction sequence‐specific primer method (PCR‐SSP) and used it to determine the HNA‐5a gene frequencies in 320 individuals from...
Paper Details
Title
Genotyping of human neutrophil antigen‐5a (Ond)
Published Date
Apr 1, 2005
Journal
Volume
15
Issue
2
Pages
115 - 117
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