Dextran-based hydrogel formed by thiol-Michael addition reaction for 3D cell encapsulation
Abstract
Cell encapsulation in three-dimensional (3D) hydrogels can mimic native cell microenvironment and plays a major role in cell-based transplantation therapies. In this contribution, a novel in situ-forming hydrogel, Dex-l-DTT hydrogel ("l" means "linked-by"), by cross-linking glycidyl methacrylate derivatized dextran (Dex-GMA) and dithiothreitol (DTT) under physiological conditions, has been developed using thiol-Michael addition reaction. The...
Paper Details
Title
Dextran-based hydrogel formed by thiol-Michael addition reaction for 3D cell encapsulation
Published Date
Apr 1, 2015
Volume
128
Pages
140 - 148
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