Genotype imputation accuracy with different reference panels in admixed populations
Abstract
Genome-wide association studies have successfully identified common variants that are associated with complex diseases. However, the majority of genetic variants contributing to disease susceptibility are yet to be discovered. It is now widely believed that multiple rare variants are likely to be associated with complex diseases. Using custom-made chips or next-generation sequencing to uncover the effects of rare variants on the disease can be...
Paper Details
Title
Genotype imputation accuracy with different reference panels in admixed populations
Published Date
Jun 1, 2014
Journal
Volume
8
Issue
S1
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Notes
History