COMPARISON OF THE LIGAND BINDING SPECIFICITY AND TRANSCRIPT TISSUE DISTRIBUTION OF ESTROGEN RECEPTORS ALPHA AND BETA

Volume: 138, Issue: 3, Pages: 863 - 870
Published: Mar 1, 1997
Abstract
The rat estrogen receptor (ER) exists as two subtypes, ER alpha and ER beta, which differ in the C-terminal ligand binding domain and in the N-terminal transactivation domain. In this study we investigated the messenger RNA expression of both ER subtypes in rat tissues by RT-PCR and compared the ligand binding specificity of the ER subtypes. Saturation ligand binding analysis of in vitro synthesized human ER alpha and rat ER beta protein...
Paper Details
Title
COMPARISON OF THE LIGAND BINDING SPECIFICITY AND TRANSCRIPT TISSUE DISTRIBUTION OF ESTROGEN RECEPTORS ALPHA AND BETA
Published Date
Mar 1, 1997
Volume
138
Issue
3
Pages
863 - 870
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