Nuclear Receptors, RXR, and the Big Bang
Abstract
Isolation of genes encoding the receptors for steroids, retinoids, vitamin D, and thyroid hormone and their structural and functional analysis revealed an evolutionarily conserved template for nuclear hormone receptors. This discovery sparked identification of numerous genes encoding related proteins, termed orphan receptors. Characterization of these orphan receptors and, in particular, of the retinoid X receptor (RXR) positioned nuclear...
Paper Details
Title
Nuclear Receptors, RXR, and the Big Bang
Published Date
Mar 1, 2014
Journal
Volume
157
Issue
1
Pages
255 - 266
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