Solution Toxicity in Soft Contact Lens Daily Wear Is Associated With Corneal Inflammation

Purpose. Contact lens-associated solution toxicity manifests as generalized, mild punctate epithelial fluorescein staining and usually is widely reported as asymptomatic, with no substantial clinical sequelae. This study examined the relationship between solution toxicity and corneal infiltrative events (CIEs) in soft contact lens daily wear. Methods. Several nonrandomized interventional clinical trials conducted between May and November 2005...