Chromosomal Radiosensitivity, Cancer Predisposition and Response to Radiotherapy

This paper briefly summarizes the research on this topic, undertaken in the Department of Cancer genetics, Paterson Institute for Cancer Research, Manchester, England, over the previous 6 years. Patients and Method: Patients with the recessively-inherited disease, ataxia-telangiectasia (A-T), who are cancer-prone and suffer severe reactions after radiotherapy, also have highly radiosensitive cells, particularly when chromosome damage is used as...