Human hololactoferrin: endocytosis and use as an iron source by the parasite Entamoeba histolytica

Volume: 151, Issue: 12, Pages: 3859 - 3871
Published: Dec 1, 2005
Abstract
Entamoeba histolytica is an enteric protozoan that exclusively infects human beings. This parasite requires iron for its metabolic functions. Lactoferrin is a mammalian glycoprotein that chelates extracellular iron on mucosal surfaces, including the surface of the large intestine, where E. histolytica initiates infection. This work examined the interaction in vitro of E. histolytica trophozoites with human hololactoferrin (iron-saturated...
Paper Details
Title
Human hololactoferrin: endocytosis and use as an iron source by the parasite Entamoeba histolytica
Published Date
Dec 1, 2005
Volume
151
Issue
12
Pages
3859 - 3871
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