Challenges in assessing regional distribution of inhaled drug in the human lungs
Abstract
Introduction: Both the total amount of drug deposited in the lungs (whole lung deposition) and the amount deposited in different lung regions (regional lung deposition) are potentially important factors that determine the safety and efficacy of inhaled drugs. Radionuclide imaging is well established for quantifying the whole lung deposition of inhaled drugs, but the assessment of regional lung deposition is less straightforward, because of the...
Paper Details
Title
Challenges in assessing regional distribution of inhaled drug in the human lungs
Published Date
May 10, 2011
Volume
8
Issue
7
Pages
841 - 855
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