Loss of BMAL1 in ovarian steroidogenic cells results in implantation failure in female mice

Significance This work demonstrates that specific peripheral clocks play unique and discrete roles in specific aspects of reproductive biology. Our use of a cell-specific conditional knockout model, in coordination with ovary transplant technology, permits examination of a peripheral clock without the impacts of off-target deletions that might indirectly impact reproductive function. In this case, we show that the molecular circadian clock,...