Semaphorins and plexins as therapeutic targets
Abstract
Semaphorins are membrane-bound or diffusible factors that regulate key cellular functions and are involved in cell-cell communication. Most of the effects of semaphorins are mediated by plexins. Work over the past decade has revealed crucial functions of the semaphorin-plexin system in mammalian physiology. It has also become clear that semaphorins and plexins have important roles in many pathophysiological processes, including cancer,...
Paper Details
Title
Semaphorins and plexins as therapeutic targets
Published Date
Aug 1, 2014
Volume
13
Issue
8
Pages
603 - 621
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