Nephropathy in a Hypercholesterolemic Mouse Model with Streptozotocin-Induced Diabetes

Volume: 26, Issue: 5-6, Pages: 351 - 361
Published: Jan 1, 2003
Abstract
<i>Background/Aims:</i> The contribution of preexisting hypercholesterolemia to diabetic nephropathy remains unclear. We assessed the impact of hypercholesterolemia on diabetic nephropathy using a double knockout (DKO) mouse, null for the low-density lipoprotein receptor <i>(Ldlr–/–)</i> and the apoB mRNA editing catalytic polypeptide 1 <i>(Apobec1–/–)</i>. <i>Methods:</i> Wild-type (WT) and DKO...
Paper Details
Title
Nephropathy in a Hypercholesterolemic Mouse Model with Streptozotocin-Induced Diabetes
Published Date
Jan 1, 2003
Volume
26
Issue
5-6
Pages
351 - 361
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