Betulinic acid induces a novel cell death pathway that depends on cardiolipin modification

Volume: 35, Issue: 4, Pages: 427 - 437
Published: Jan 28, 2016
Abstract
Cancer is associated with strong changes in lipid metabolism. For instance, normal cells take up fatty acids (FAs) from the circulation, while tumour cells generate their own and become dependent on de novo FA synthesis, which could provide a vulnerability to target tumour cells. Betulinic acid (BetA) is a natural compound that selectively kills tumour cells through an ill-defined mechanism that is independent of BAX and BAK, but depends on...
Paper Details
Title
Betulinic acid induces a novel cell death pathway that depends on cardiolipin modification
Published Date
Jan 28, 2016
Journal
Volume
35
Issue
4
Pages
427 - 437
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.