Impact of the HIV Tat C30C31S dicysteine substitution on neuropsychological function in patients with clade C disease

Volume: 20, Issue: 6, Pages: 627 - 635
Published: Nov 1, 2014
Abstract
Previous animal studies have identified a C31S residue substitution in the C30C31 dicysteine motif of the Tat protein that is associated with reduced neurovirulence in clade C human immunodeficiency virus (HIV). However, clinical studies of patients infected with clade C HIV have reported significant levels of cognitive impairment. To date, no study has specifically examined cognitive function in clade C-infected patients as a function of the...
Paper Details
Title
Impact of the HIV Tat C30C31S dicysteine substitution on neuropsychological function in patients with clade C disease
Published Date
Nov 1, 2014
Volume
20
Issue
6
Pages
627 - 635
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