Functional roles of the bone morphogenetic protein system in thyrotropin signaling in porcine thyroid cells

Volume: 327, Issue: 4, Pages: 1124 - 1130
Published: Feb 1, 2005
Abstract
We uncovered a new regulation of thyrocyte function by bone morphogenetic protein (BMP) under the influence of thyrotropin (TSH) using primary culture of porcine thyrocytes. The BMP type I receptors, ALK-2 (ActRIA), -3 (BMPRIA), and -6 (BMPRIB), were expressed in porcine thyrocytes, while ALK-6 was not detected in human thyroid. Treatment with BMP-2, -4, -6, -7, and TGF-β1 exhibited a dose-dependent suppression of DNA synthesis by porcine...
Paper Details
Title
Functional roles of the bone morphogenetic protein system in thyrotropin signaling in porcine thyroid cells
Published Date
Feb 1, 2005
Volume
327
Issue
4
Pages
1124 - 1130
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.