Thermodynamic Characterization of Proteins with Electrically Actuated DNA Nanolevers

Volume: 106, Issue: 2
Published: Jan 28, 2014
Abstract
switchSENSE is a novel chip-based bioanalytical method that employs electrically switchable DNA nanolevers as molecular probes. While the nanolevers are driven to oscillate on the surface of microelectrodes by alternating electric fields, their orientation-switching is detected by time-resolved single photon counting. By measuring the molecular dynamics of the switching process it is possible to gauge the hydrodynamic properties of analyte...
Paper Details
Title
Thermodynamic Characterization of Proteins with Electrically Actuated DNA Nanolevers
Published Date
Jan 28, 2014
Volume
106
Issue
2
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