Activated pancreatic stellate cells can impair pancreatic islet function in mice

Volume: 120, Issue: 3, Pages: 169 - 180
Published: Apr 8, 2015
Abstract
Background. Pancreatic or islet fibrosis is often associated with activated pancreatic stellate cells (PSCs). PSCs are considered not only to promote fibrosis, but also to be associated with glucose intolerance in some diseases. We therefore evaluated morphological and functional relationships between islets and PSCs in the normal mouse pancreas and transplanted islets. Methods. Immunohistochemistry was used to map the presence of PSCs in the...
Paper Details
Title
Activated pancreatic stellate cells can impair pancreatic islet function in mice
Published Date
Apr 8, 2015
Volume
120
Issue
3
Pages
169 - 180
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