RATES OF DECLINE DISTINGUISH ALZHEIMER'S DISEASE AND MILD COGNITIVE IMPAIRMENT RELATIVE TO NORMAL AGING: INTEGRATING COGNITION AND BRAIN FUNCTION

Increasing age is the strongest risk factor for Alzheimer's disease (AD). Yet, departure from normal age-related decline for established markers of AD including memory, cognitive decline and brain function deficits, has not been quantified.We examined the cross-sectional estimates of the "rate of decline" in cognitive performance and psychophysiological measures of brain function over age in AD, preclinical (subjective memory complaint-SMC, Mild...