Functional Role of Monocytes and Macrophages for the Inflammatory Response in Acute Liver Injury
Abstract
Different etiologies such as drug toxicity, acute viral hepatitis B, or acetaminophen poisoning can cause acute liver injury or even acute liver failure (ALF). Excessive cell death of hepatocytes in the liver is known to result in a strong hepatic inflammation. Experimental murine models of liver injury highlighted the importance of hepatic macrophages, so-called Kupffer cells, for initiating and driving this inflammatory response by releasing...
Paper Details
Title
Functional Role of Monocytes and Macrophages for the Inflammatory Response in Acute Liver Injury
Published Date
Jan 1, 2012
Journal
Volume
3
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