SREBP-1c Gene Silencing can Decrease Lipid Deposits in Bovine Hepatocytes Cultured <b><i>in Vitro</i></b>
Abstract
Fatty liver is a major metabolic disorder that occurs during early lactation in high-producing dairy cows. Sterol regulatory element-binding protein-1c (SREBP-1c) is an important transcription factor that regulates lipid synthesis by regulating the expression of lipid metabolism genes.In this study, we reduced the expression of SREBP-1c by adenovirus-mediated SREBP-1c with a low expression vector (AD-GFP-SREBP-1c) to study the effects of...
Paper Details
Title
SREBP-1c Gene Silencing can Decrease Lipid Deposits in Bovine Hepatocytes Cultured <b><i>in Vitro</i></b>
Published Date
Jan 1, 2014
Volume
33
Issue
5
Pages
1568 - 1578
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