Efficacy of ABT-116, an antagonist of transient receptor potential vanilloid type 1, in providing analgesia for dogs with chemically induced synovitis

Volume: 73, Issue: 1, Pages: 19 - 26
Published: Jan 1, 2012
Abstract
Objective —To investigate the ability of ABT-116 (a proprietary antagonist of transient receptor potential vanilloid type 1) administered at 2 doses to attenuate lameness in dogs with experimentally induced urate synovitis. Animals —8 purpose-bred mixed-breed dogs. Procedures —In a 4-way crossover study, dogs orally received each of low-dose ABT-116 treatment (LDA; 10 mg/kg), high-dose ABT-116 treatment (HDA; 30 mg/kg), firocoxib (5 mg/kg), and...
Paper Details
Title
Efficacy of ABT-116, an antagonist of transient receptor potential vanilloid type 1, in providing analgesia for dogs with chemically induced synovitis
Published Date
Jan 1, 2012
Volume
73
Issue
1
Pages
19 - 26
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