The effect of ursodeoxycholic acid on oxidative stress level and DNase activity in rat liver after bile duct ligation
Abstract
Accumulation of hydrophobic bile acids (BAs) during cholestasis plays an important role in apoptosis initiation as well as oxidative stress increase in liver cells. Ursodeoxycholic acid (UDCA) acts as a protector in BA-induced cell injury.The aim of the study was to evaluate the effect of UDCA on oxidative stress level and DNase I and II activity caused by liver injury in bile duct ligation (BDL) rats.Wistar rats were divided in four groups:...
Paper Details
Title
The effect of ursodeoxycholic acid on oxidative stress level and DNase activity in rat liver after bile duct ligation
Published Date
Mar 2, 2012
Journal
Volume
36
Issue
2
Pages
141 - 148
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