Popliteal lymph node assay: facts and perspectives.
Abstract
The popliteal lymph node assay (PLNA) derives from the hypothesis that some supposedly immune-mediated adverse effects induced by certain pharmaceuticals involve a mechanism resembling a graft-versus-host reaction. The injection of many but not all of these compounds into the footpad of mice or rats produces an increase in the weight and/or cellularity of the popliteal lymph node in the treated limb (direct PLNA). Some of the compounds known to...
Paper Details
Title
Popliteal lymph node assay: facts and perspectives.
Published Date
Nov 1, 2005
Volume
25
Issue
6
Pages
451 - 458
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