A new 3D reconstituted human corneal epithelium model as an alternative method for the eye irritation test
Abstract
Many efforts are being made to develop new alternative in vitro test methods for the eye irritation test. Here we report a new reconstructed human corneal epithelial model (MCTT HCE model) prepared from primary-cultured human limbal epithelial cells as a new alternative in vitro eye irritation test method. In histological and immunohistochemical observation, MCTT HCE model displayed a morphology and biomarker expressions similar to intact human...
Paper Details
Title
A new 3D reconstituted human corneal epithelium model as an alternative method for the eye irritation test
Published Date
Feb 1, 2011
Journal
Volume
25
Issue
1
Pages
403 - 410
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