Abstract 529: nc886, a noncoding RNA of anti-proliferative role, is suppressed by CpG DNA methylation in human gastric cancer

Volume: 74, Pages: 529 - 529
Published: Oct 1, 2014
Abstract
nc886, a novel type of non-coding RNA, was initially identified as a microRNA precursor or a vault RNA, but it has been shown to be distinct from them and rather to be a cellular RNA ligand and inhibitor of PKR (Protein Kinase RNA-activated). PKR9s roles in viral infection, cellular stresses, and cancer are well documented. nc886 has also been suggested to be a tumor suppressor, mainly inferred by its expression pattern as well as its genomic...
Paper Details
Title
Abstract 529: nc886, a noncoding RNA of anti-proliferative role, is suppressed by CpG DNA methylation in human gastric cancer
Published Date
Oct 1, 2014
Volume
74
Pages
529 - 529
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