Glial cell-expressed mechanosensitive channel TRPV4 mediates infrasound-induced neuronal impairment
Abstract
Vibroacoustic disease, a progressive and systemic disease, mainly involving the central nervous system, is caused by excessive exposure to low-frequency but high-intensity noise generated by various heavy transportations and machineries. Infrasound is a type of low-frequency noise. Our previous studies demonstrated that infrasound at a certain intensity caused neuronal injury in rats but the underlying mechanism(s) is still largely unknown....
Paper Details
Title
Glial cell-expressed mechanosensitive channel TRPV4 mediates infrasound-induced neuronal impairment
Published Date
Sep 4, 2013
Journal
Volume
126
Issue
5
Pages
725 - 739
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Notes
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