Abstract B6: Cadherin switching, multicellular aggregate dynamics and metastatic success

Epithelial Ovarian Carcinoma (EOC) is the fifth leading cause of women's cancer-related death and deadliest of all gynecological cancers with 22,240 new and 14,230 fatal cases predicted in 2013 (American Cancer Society Estimates, 2013), primarily due to detection at late metastatic, prognostically poor stages of the disease. As opposed to other malignancies, EOC metastasis occurs by shedding of cancer cells from the primary tumor directly into...