Generation of Novel Hybrid Aptamer–Molecularly Imprinted Polymeric Nanoparticles
Abstract
A strategy to exploit aptamers as recognition elements of molecularly imprinted polymeric nanoparticles (AptaMIP NPs) is presented, via modification of the chemical structure of the DNA. It is demonstrated that the introduction of this modified aptamer monomer results in an increase of the affinity of the produced MIP NPs, without altering their physical properties such as size, shape, or...
Paper Details
Title
Generation of Novel Hybrid Aptamer–Molecularly Imprinted Polymeric Nanoparticles
Published Date
Jan 1, 2015
Journal
Volume
27
Issue
4
Pages
750 - 758
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History