Associations between white matter microstructure and amyloid burden in preclinical Alzheimer's disease: A multimodal imaging investigation
Abstract
Some cognitively healthy individuals develop brain amyloid accumulation, suggestive of incipient Alzheimer's disease (AD), but the effect of amyloid on other potentially informative imaging modalities, such as Diffusion Tensor Imaging (DTI), in characterizing brain changes in preclinical AD requires further exploration. In this study, a sample (N = 139, mean age 60.6, range 46 to 71) from the Wisconsin Registry for Alzheimer's Prevention (WRAP),...
Paper Details
Title
Associations between white matter microstructure and amyloid burden in preclinical Alzheimer's disease: A multimodal imaging investigation
Published Date
Jan 1, 2014
Journal
Volume
4
Pages
604 - 614
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