Serine proteases of the human immune system in health and disease
Abstract
Serine proteases form a large family of protein-cleaving enzymes that play an essential role in processes like blood coagulation, apoptosis and inflammation. Immune cells express a wide variety of serine proteases such as granzymes in cytotoxic lymphocytes, neutrophil elastase, cathepsin G and proteinase 3 in neutrophils and chymase and tryptase in mast cells. Regulation of proteolysis induced by these serine proteases is essential to prevent...
Paper Details
Title
Serine proteases of the human immune system in health and disease
Published Date
Jul 1, 2010
Journal
Volume
47
Issue
11-12
Pages
1943 - 1955
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Notes
History