Circadian rhythm of melatonin and prostaglandin in modulation of stress‐induced gastric mucosal lesions in rats

Volume: 16, Issue: s2, Pages: 29 - 34
Published: Apr 1, 2002
Abstract
We previously demonstrated the circadian variation of water-immersion restraint stress (WRS)-induced gastric mucosal lesions in rats.To investigate the roles of melatonin and prostaglandin in the gastric mucosa in circadian modulation of WRS.Fasted rats were subjected to 4-h WRS during both the diurnal and nocturnal phases of a light/dark cycle. Mucosal lesions, serum melatonin concentrations, mucosal generation of prostaglandin E2 (PGE2) and...
Paper Details
Title
Circadian rhythm of melatonin and prostaglandin in modulation of stress‐induced gastric mucosal lesions in rats
Published Date
Apr 1, 2002
Volume
16
Issue
s2
Pages
29 - 34
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