Single drop microextraction—Development, applications and future trends

Single drop microextraction (SDME) has emerged over the last 10–15 years as one of the simplest and most easily implemented forms of micro-scale sample cleanup and preconcentration. In the most common arrangement, an ordinary chromatography syringe is used to suspend microliter quantities of extracting solvent either directly immersed in the sample, or in the headspace above the sample. The same syringe is then used to introduce the solvent and...