Toward a unified nomenclature for mammalian ADP-ribosyltransferases
Abstract
ADP-ribosylation is a post-translational modification of proteins catalyzed by ADP-ribosyltransferases. It comprises the transfer of the ADP-ribose moiety from NAD+ to specific amino acid residues on substrate proteins or to ADP-ribose itself. Currently, 22 human genes encoding proteins that possess an ADP-ribosyltransferase catalytic domain are known. Recent structural and enzymological evidence of poly(ADP-ribose)polymerase (PARP) family...
Paper Details
Title
Toward a unified nomenclature for mammalian ADP-ribosyltransferases
Published Date
Apr 1, 2010
Volume
35
Issue
4
Pages
208 - 219
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