Shape-dependent cell migration and focal adhesion organization on suspended and aligned nanofiber scaffolds
Abstract
In the body, cells dynamically respond to chemical and mechanical cues from the extracellular matrix (ECM), yet precise mechanisms by which biophysical parameters (stiffness, topography and alignment) affect cell behavior remain unclear. Here, highly aligned and suspended multilayer polystyrene (PS) nanofiber scaffolds are used to study biophysical influences on focal adhesion complex (FAC) arrangement and associated migration behavior of mouse...
Paper Details
Title
Shape-dependent cell migration and focal adhesion organization on suspended and aligned nanofiber scaffolds
Published Date
Jul 1, 2013
Journal
Volume
9
Issue
7
Pages
7169 - 7177
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Notes
History