Mechanisms of HBV-related hepatocarcinogenesis

Volume: 52, Issue: 4, Pages: 594 - 604
Published: Apr 1, 2010
Abstract
The hepatitis B virus (HBV) is a small enveloped DNA virus, which primarily infects hepatocytes and causes acute and persistent liver disease. Epidemiological studies have provided overwhelming evidence for a causal role of chronic HBV infection in the development of hepatocellular carcinoma, but the molecular mechanisms underlying virally-induced tumourigenesis remain largely debated. In the absence of a dominant oncogene encoded by the HBV...
Paper Details
Title
Mechanisms of HBV-related hepatocarcinogenesis
Published Date
Apr 1, 2010
Volume
52
Issue
4
Pages
594 - 604
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