Anti-cancer effect of Cassia auriculata leaf extract in vitro through cell cycle arrest and induction of apoptosis in human breast and larynx cancer cell lines
Abstract
The in vitro anti‐cancer effect of Cassia auriculata leaf extract (CALE) was evaluated in human breast adenocarcinoma MCF‐7 and human larynx carcinoma Hep‐2 cell lines. CALE preferentially inhibited the growth of both the cell lines in a dose‐dependent manner with IC 50 values of 400 and 500 μg for MCF‐7 and Hep‐2 cells, respectively. The results showed the anti‐cancer action is due to nuclear fragmentation and condensation, associated with the...
Paper Details
Title
Anti-cancer effect of Cassia auriculata leaf extract in vitro through cell cycle arrest and induction of apoptosis in human breast and larynx cancer cell lines
Published Date
Feb 1, 2009
Journal
Volume
33
Issue
2
Pages
127 - 134
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