A Placebo-Controlled Randomized Trial of Warfarin in Idiopathic Pulmonary Fibrosis

Volume: 186, Issue: 1, Pages: 88 - 95
Published: Jul 1, 2012
Abstract
Rationale: Animal and human studies support the importance of the coagulation cascade in pulmonary fibrosis.Objectives: In a cohort of subjects with progressive idiopathic pulmonary fibrosis (IPF), we tested the hypothesis that treatment with warfarin at recognized therapeutic doses would reduce rates of mortality, hospitalization, and declines in FVC.Methods: This was a double-blind, randomized, placebo-controlled trial of warfarin targeting an...
Paper Details
Title
A Placebo-Controlled Randomized Trial of Warfarin in Idiopathic Pulmonary Fibrosis
Published Date
Jul 1, 2012
Volume
186
Issue
1
Pages
88 - 95
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