Uric acid as a danger signal in gout and its comorbidities
Abstract
Uric acid is a waste product of purine catabolism. This molecule comes to clinical attention when it nucleates to form crystals of monosodium urate (MSU) in joints or other tissues, and thereby causes the inflammatory disease of gout. Patients with gout frequently suffer from a number of comorbid conditions including hypertension, diabetes mellitus and cardiovascular disease. Why MSU crystals trigger inflammation and are associated with...
Paper Details
Title
Uric acid as a danger signal in gout and its comorbidities
Published Date
Sep 4, 2012
Journal
Volume
9
Issue
1
Pages
13 - 23
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