Anti-tumor effects of a novel chimeric peptide on S180 and H22 xenografts bearing nude mice
Abstract
In recent years, many endogenous peptides have been identified by screening combinatory phage display peptide library, which play important roles in the process of angiogenesis. A heptapeptide, ATWLPPR, binds specifically to NRP-1 and selectively inhibits VEGF165 binding to VEGFR-2. Another heptapeptide, NLLMAAS, blocks both Ang-1 and Ang-2 binding to Tie-2 in a dose-dependent manner. In the present study, we aimed to connect ATWLPPR (V1) with...
Paper Details
Title
Anti-tumor effects of a novel chimeric peptide on S180 and H22 xenografts bearing nude mice
Published Date
May 1, 2010
Journal
Volume
31
Issue
5
Pages
850 - 864
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