Mechanisms of uric acid crystal-mediated autoinflammation.
Abstract
Gout is an arthritis characterized by elevated uric acid in the bloodstream. In this condition, crystals of uric acid are formed and accumulate in the synovial fluids. Crystal deposition leads to acute inflammation, which is associated with the spontaneous resolution of the disease. Recent studies have led to significant advances in the understanding of the basic biology of crystal-mediated inflammation. Uric acid has been identified as a danger...
Paper Details
Title
Mechanisms of uric acid crystal-mediated autoinflammation.
Published Date
Jan 1, 2010
Journal
Volume
233
Issue
1
Pages
218 - 232
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