INS-1 cells inhibit the production of extracellular matrix from pancreatic stellate cells
Abstract
In type 2 diabetes mellitus, pancreatic stellate cells (PSCs) are present within and surrounding pancreatic islets and may cause progressive fibrosis and deterioration of pancreatic beta cell function. However, it is unknown whether pancreatic beta cells influence the biological behavior of PSCs. In the present study, we examined the impact of pancreatic beta cells on the proliferation, migration and extracellular matrix (ECM) production of...
Paper Details
Title
INS-1 cells inhibit the production of extracellular matrix from pancreatic stellate cells
Published Date
Jun 1, 2014
Volume
45
Issue
3
Pages
321 - 327
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