Flavanone silibinin treatment attenuates nitrogen mustard-induced toxic effects in mouse skin
Abstract
Currently, there is no effective antidote to prevent skin injuries by sulfur mustard (SM) and nitrogen mustard (NM), which are vesicating agents with potential relevance to chemical warfare, terrorist attacks, or industrial/laboratory accidents. Our earlier report has demonstrated the therapeutic efficacy of silibinin, a natural flavanone, in reversing monofunctional alkylating SM analog 2-chloroethyl ethyl sulfide-induced toxic effects in mouse...
Paper Details
Title
Flavanone silibinin treatment attenuates nitrogen mustard-induced toxic effects in mouse skin
Published Date
May 1, 2015
Volume
285
Issue
1
Pages
71 - 78
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