Endogenous CNTF mediates stroke-induced adult CNS neurogenesis in mice
Abstract
Focal brain ischemia in adult rats rapidly and robustly induces neurogenesis in the subventricular zone (SVZ) but there are few and inconsistent reports in mice, presenting a hurdle to genetically investigate the endogenous neurogenic regulators such as ciliary neurotrophic factor (CNTF). Here, we first provide a platform for further studies by showing that middle cerebral artery occlusion in adult male C57BL/6 mice robustly enhances...
Paper Details
Title
Endogenous CNTF mediates stroke-induced adult CNS neurogenesis in mice
Published Date
Jan 1, 2013
Journal
Volume
49
Pages
68 - 78
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