Diagnostic guidelines for IgG4-related disease with a focus on histopathological criteria

IgG4-related disease (IgG4-RD) is an under recognized, protean, multiorgan fibro-inflammatory condition of unknown aetiology that is defined by its unique histopathological features, that are fairly similar regardless of the affected organ. Patients with IgG4-RD also share certain clinical features: a tendency for formation of mass lesion(s), frequent elevations in their serum IgG4 concentration, as well as an excellent response to...