Unbiased evaluation of bioactive secondary metabolites in complex matrices
Abstract
The majority of bioactive principles in a complex matrix such as natural products and botanical medicines are secondary rather than primary metabolites. In addition to being chemically diverse, the bioactivity of an ethnobotanical can comprise from one to several bioactive compounds, present in a complex mixture. Conventional discovery efforts utilize bioassay-guided fractionation (BGF) to isolate individual active compounds. When applied to...
Paper Details
Title
Unbiased evaluation of bioactive secondary metabolites in complex matrices
Published Date
Oct 1, 2012
Journal
Volume
83
Issue
7
Pages
1218 - 1225
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