The evolutionary history of lethal metastatic prostate cancer.

Nature64.80
Volume: 520, Issue: 7547, Pages: 353 - 357
Published: Apr 16, 2015
Abstract
Cancers emerge from an ongoing Darwinian evolutionary process, often leading to multiple competing subclones within a single primary tumour. This evolutionary process culminates in the formation of metastases, which is the cause of 90% of cancer-related deaths. However, despite its clinical importance, little is known about the principles governing the dissemination of cancer cells to distant organs. Although the hypothesis that each metastasis...
Paper Details
Title
The evolutionary history of lethal metastatic prostate cancer.
Published Date
Apr 16, 2015
Journal
Volume
520
Issue
7547
Pages
353 - 357
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