Electromechanical window negativity in genotyped long-QT syndrome patients: relation to arrhythmia risk
Abstract
Prolonged and dispersed left-ventricular (LV) contraction is present in patients with long-QT syndrome (LQTS). Electrical and mechanical abnormalities appear most pronounced in symptomatic individuals. We focus on the 'electromechanical window' (EMW; duration of LV-mechanical systole minus QT interval) in patients with genotyped LQTS. Profound EMW negativity heralds torsades de pointes in animal models of drug-induced LQTS.We included 244 LQTS...
Paper Details
Title
Electromechanical window negativity in genotyped long-QT syndrome patients: relation to arrhythmia risk
Published Date
Sep 9, 2014
Journal
Volume
36
Issue
3
Pages
179 - 186
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