T1979 Pepsinogen II As Marker of Inflammation in H.P Infection and in NSAIDs Damage

NH4Cl prepulse followed by a Na+-free solution. Alkalinization in Na+-free solution represents intracellular acid production and eliminates the possibility of contribution by the Na+/ H+ proteins. Studies were done in the presence or absence of indomethacin (100μM) or acetylsalicylic acid (ASA) (100-500μM). Results: In the presence of indomethacin, a rapid decrease in pHi is seen upon the removal of Na+, followed by an immediate rise in pHi,...