Lecithin Cholesterol Acyltransferase: An Anti- or Pro-atherogenic Factor?
Abstract
Lecithin cholesterol acyl transferase (LCAT) is a plasma enzyme that esterifies cholesterol and raises high-density lipoprotein cholesterol, but its role in atherosclerosis is not clearly established. Studies of various animal models have yielded conflicting results, but studies done in rabbits and non-human primates, which more closely simulate human lipoprotein metabolism, indicate that LCAT is likely atheroprotective. Although suggestive,...
Paper Details
Title
Lecithin Cholesterol Acyltransferase: An Anti- or Pro-atherogenic Factor?
Published Date
Feb 18, 2011
Volume
13
Issue
3
Pages
249 - 256
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